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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NMNAT1 All Species: 5.45
Human Site: T145 Identified Species: 9.23
UniProt: Q9HAN9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAN9 NP_073624.2 279 31932 T145 K K S L E P K T K A V P K V K
Chimpanzee Pan troglodytes XP_001168527 254 29013 P124 E P K T K A V P K V K L L C G
Rhesus Macaque Macaca mulatta XP_001118727 179 20456 P49 E P K T K A V P K V K L L C G
Dog Lupus familis XP_536739 279 31883 T145 K K S L E P K T K D V P K V K
Cat Felis silvestris
Mouse Mus musculus Q9EPA7 285 32337 K145 P Q K P Q E P K P T G V P K V
Rat Rattus norvegicus Q0HA29 307 34426 T145 Y Q N S N V P T K P T A A K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507826 272 31049 I142 D L L E S F G I P N L W K K E
Chicken Gallus gallus XP_417605 284 32371 P148 I K K K N Q S P D G K N V P Q
Frog Xenopus laevis NP_001091188 278 32072 A146 S Y L Q E N K A V P Q V K L L
Zebra Danio Brachydanio rerio Q6PC93 304 34191 V145 Q N T V N K S V A I K F W G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651315 389 43777 E158 G G G G D D G E N T H L P G W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91851 223 25149 V93 T W T R T I D V L R H H R E L
Sea Urchin Strong. purpuratus XP_783084 287 32645 A156 N D T E V D D A Y G A P N L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53204 395 44891 E156 T K K L Q D P E K L P L I I V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 62 86.3 N.A. 80.6 28.6 N.A. 63.7 69.7 60.9 26.9 N.A. 33.9 N.A. 26.1 47.3
Protein Similarity: 100 89.6 62.3 92.1 N.A. 89.4 48.5 N.A. 76.3 82 76.3 46.7 N.A. 48 N.A. 44 67.9
P-Site Identity: 100 6.6 6.6 93.3 N.A. 0 13.3 N.A. 6.6 6.6 20 6.6 N.A. 0 N.A. 0 6.6
P-Site Similarity: 100 20 20 93.3 N.A. 13.3 26.6 N.A. 20 13.3 26.6 26.6 N.A. 6.6 N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 15 0 15 8 8 8 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % C
% Asp: 8 8 0 0 8 22 15 0 8 8 0 0 0 0 0 % D
% Glu: 15 0 0 15 22 8 0 15 0 0 0 0 0 8 8 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % F
% Gly: 8 8 8 8 0 0 15 0 0 15 8 0 0 15 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 15 8 0 0 0 % H
% Ile: 8 0 0 0 0 8 0 8 0 8 0 0 8 8 8 % I
% Lys: 15 29 36 8 15 8 22 8 43 0 29 0 29 22 22 % K
% Leu: 0 8 15 22 0 0 0 0 8 8 8 29 15 15 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 8 0 22 8 0 0 8 8 0 8 8 0 8 % N
% Pro: 8 15 0 8 0 15 22 22 15 15 8 22 15 8 0 % P
% Gln: 8 15 0 8 15 8 0 0 0 0 8 0 0 0 8 % Q
% Arg: 0 0 0 8 0 0 0 0 0 8 0 0 8 0 0 % R
% Ser: 8 0 15 8 8 0 15 0 0 0 0 0 0 0 0 % S
% Thr: 15 0 22 15 8 0 0 22 0 15 8 0 0 0 0 % T
% Val: 0 0 0 8 8 8 15 15 8 15 15 15 8 15 15 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 8 8 0 8 % W
% Tyr: 8 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _